Feline Acromegaly

Acromegaly

Acromegaly is due to excessive production of growth hormone (GH), generally by a pituitary GH-secreting adenoma. Its prevalence is estimated at 40-130 cases per million inhabitants. Acromegaly is characterized by slowly progressive acquired somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The rheumatologic, cardiovascular, respiratory, and metabolic...

Acromegaly

Acromegaly is a comparatively rare disease but has attracted the notice of clinicians all over the world on account of the peculiar features associated with it. Within recent years, the finding of an adenomatous growth in the pituitary gland in cases of acromegaly lias focussed a great deal of interest around the subject. This monograph of Dr. Atkinson is therefore likely to be well received by...

Acromegaly.

Acromegaly Ariel

In the majority of cases, acromegaly is due to GH hypersecretion by a somatotroph pituitary tumor. The etiology of acromegaly is not known, and may be related to GHRH hypersecretion, intn’nsic pituitary defect, or a combination thereof: Recent physiologic data and molecular biology techniques provide insights into the pathophysiology of this condition. Treatment options include surgery, radiati...

Familial acromegaly - case study of two sisters with acromegaly.

In the majority of cases, acromegaly is sporadic. However, it can also occur in a familial setting as a component of MEN-1, MEN-4, Carney complex (CNC) or as the extremely rare syndrome of isolated familial somatotropinoma (IFS), the latter belonging to familial isolated pituitary adenomas (FIPA). The diagnosis of IFS is based on the recognition of acromegaly/gigantism in at least two family me...